VAXNEUVANCE

FDA Approved: 2021

Vaccine Type(s)

PCV

What you can expect

These are the most commonly reported short-term reactions based on the manufacturer's official package insert.

⚠️ Limited data — rates may not fully reflect real-world experience

Infants & Toddlers

Irritability

Very common

More than 5 in 10

Increased sleep

Less common

About 1 in 10

Injection site reactions

Less common

Pain, redness, or swelling where the shot is given

About 1 in 10

Fever

Less common

About 1 in 10

Decreased appetite

Less common

About 1 in 10

Injection site induration

Less common

About 1 in 10

Firm, hardened area under the skin

Children (5-17)

Injection site reactions

Very common

Pain, redness, or swelling where the shot is given

More than 5 in 10

Muscle pain

Less common

About 1 in 10

Fatigue

Less common

About 1 in 10

Headache

Less common

About 1 in 10

Adults (18-49)

Injection site reactions

Very common

Pain, redness, or swelling where the shot is given

More than 5 in 10

Fatigue

Common

More than 3 in 10

Muscle pain

Less common

About 1 in 10

Headache

Less common

About 1 in 10

Joint pain

Less common

About 1 in 10

Adults (50+)

Injection site reactions

Very common

Pain, redness, or swelling where the shot is given

More than 5 in 10

Muscle pain

Less common

About 1 in 10

Fatigue

Less common

About 1 in 10

Headache

Less common

About 1 in 10

Source: FDA-approved package insert

See the Full Picture

Knowing what’s common is just the start.

  • Compare reactions across brands
  • See what shows up when vaccines are given together
  • Understand what that means for you or your family